Next Generation Viral Hepatitis B and C vaccine development in plants and algae using advanced biotechnological tools
Project Acronym: SmartVac
Duration: 59 months
(03/06/2019-30/04/2024)
Budget: 1.554.170,10 euro
Project financed from the Research Program funds associated with EEA Grants 2014-2021 and managed by UEFISCDI
The bilateral partnership was essential to the successful implementation of this highly-interdisciplinary study. The project required expert knowledge in (i) HBV/HCV virology, protein structure and bioinformatics (provided by the Project Promoter, the Institute of Biochemistry in Romania); (ii) plant and algae biotechnologies (provided by the Norwegian partner, NIBIO) and (iii) immunology and vaccine development (provided by the “Cantacuzino” Institute in Romania). Although not eligible for funding, the Center for Infection and Immunity of Lille, a traditional collaborator of the Project Promoter, was also partner in this consortium, contributing with the unique expertise in HCV virology and original reagents (in house made HCV monoclonal antibodies and expression plasmids that are not commercially available).
The Institute of Biochemistry of the Romanian Academy (IBAR), Romania (Project Promoter);
Team:
Norica Nichita, PhD, CS1 (project director)
Catalin Lazar, PhD, CS2
Costin-Ioan Popescu, PhD, CS2
Olivia Mihaela Dobrica, PhD, CS
Ana-Maria Pantazica, PhD, CS
Lia-Maria Cucos, CS
The Norwegian Institute of Bioeconomy Research (NIBIO), Norway (P1);
Team:
Jihong Liu-Clarke, PhD, Prof. (project responsible)
Ralph Bock, PhD, Prof.
Hanne Skomedal, PhD, Prof.
Lisa Paruch, PhD
Andre Eerde, PhD
Igor Yakovlev, PhD
Inger Heldal, ing.
Kari Skjånes, T1
Hege Steen, T1
Sissel Haugslien, T1
The “Cantacuzino” National Institute for Medico-Military Research and Development (INCDMM "Cantacuzino"), Romania (P2);
Team:
Crina Stavaru, PhD, CS1 (project responsible)
Adrian Onu, PhD, CS1
Adriana Costache, PhD, CS3
Iuliana Caras, PhD, CS3
Claudiu Gal, CS
Vlad Tofan, ACS
Catalin Tucureanu, CS
Ene Vlase, CS
Doina Proteasa, T1
Viorica Adras, T1
The Center for Infection and Immunity of Lille (CIIL), France (P3); Jean Dubuisson, PhD, Prof. (project responsible)
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